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    Oral contraceptives pose little risk of stroke

     

    Oral contraceptives pose little risk of stroke


    (96/08/30) MALDEN (HealthGate) - For those of you who remember the warnings in the 1960's and 1970's that birth control pills might be associated with stroke, take heart. Two new international studies by the World Health Organization (WHO) published in this week's Lancet have found little cause for alarm.

    One study, which looked at ischemic strokes (the type of stroke where there is a decreased blood flow to the brain) compared 697 female stroke victims between the ages of 20 - 44 with 1,962 female controls in 21 centers in Africa, Asia, Europe, and Latin America. Researchers found that the incidence of this type of stroke and its connection to oral contraceptive use was minimal.

    The other study examined hemorrhagic strokes (which are characterized by uncontrolled bleeding) as well as reviewing other types of strokes. A total of 1,068 women who had hemorrhagic stroke and 2,910 women who did not have stroke were assessed, as well as an overall review of 2,198 cases and 6,086 controls for all types of stroke. Although there was a slightly increased risk of hemorrhagic stroke in women over age 35, there was no increase for women under 35. However, users who had a history of hypertension had significantly higher risk (10 to 15 fold) of hemorrhagic stroke than those who did not use oral contraceptives and had no history of hypertension.

    Researchers also found that women using pills which contained low amounts of estrogen seemed to have less risk of stroke. This corroborates the prevailing wisdom that high doses of estrogen created health risks when oral contraceptives were first introduced over thirty years ago. Today's pills are a combination of low doses of estrogen and progestin, a synthetic form of the hormone progesterone.

    Both studies agreed that contraceptive users with the lowest risk of stroke were under age 35, and did not smoke or have high blood pressure.

     






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