category: Antibiotics

Generic Seromycin

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generic seromycin
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$5.00

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generic seromycin
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$5.50

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    Seromycin
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    Diabetes and Cholesterol-Lowering Medication

     

    Diabetes and Cholesterol-Lowering Medication
    Should You Be Concerned?

    Although one of the medications used for treating high cholesterol was recently taken off the market, these medications are generally safe and effective. People with diabetes have a high risk of developing coronary artery disease (CAD) blocked arteries in the heart that may cause heart attacks, angina, or death. Elevated blood lipid levels (cholesterol and triglycerides) also increase the risk of CAD. Since high blood lipid levels are common in people with diabetes, many diabetic patients are on lipid-lowering medication.

    Recently one of these medications (Baycol cerivastatin) was taken off the market because of potentially life-threatening side effects. It was reportedly associated with 387 cases of severe muscle damage and with 31 possibly related deaths. Baycol is the newest member of the commonly used group of medications called "statins". The withdrawal of Baycol has caused many people with diabetes to be concerned about other lipid-lowering medications that they take. Some people who were on Baycol are now reluctant to take another statin.

    You can be reassured that none of the other statins have been taken off the market, and these drugs have been available for many years. They include lovastatin (Mevacor), simvastatin (Zocor), pravastatin (Pravachol), fluvastatin (Lescol) and atorvastatin ( Lipitor). While no medication is entirely free of side effects, large studies have proven that the risk of CAD can be lessened in people with diabetes with the use of these medications.

    Here are some guidelines and general information for people with diabetes who have elevated blood lipid levels:

    A diet that is low in saturated fat and total calories is important for people with diabetes. You, your doctor and your nutritionist should work together to determine your individual daily nutrition plan.

    In many cases, blood lipid levels will decrease if the blood glucose (sugar) can be kept under good control.

    A program of regular moderate exercise (such as brisk daily walking for 20 minutes or more) is very helpful in lowering blood lipids and glucose.

    Many people with diabetes will still need a lipid-lowering medication, even if they are following a proper nutrition and exercise plan.

    In general, lipid-lowering medications are very safe. For example, statins have been studied in thousands of people with diabetes and are safe and very effective. This is true for the other major type of lipid- lowering medications, the fibrates, which are used mostly for high triglycerides. Gemfibrozil (Lopid) and Fenfibrate (Tricor) are the currently available fibrates.

    As noted, Baycol was taken off the market because of severe muscle damage. This complication was noted in a far higher rate with Baycol than with the other statins. Muscle damage (rhabdomyolysis) is most commonly seen if a statin is taken together with a fibrate.

    Fibrates are also generally safe drugs and sometimes may need to be given together with a statin but if this combination is used, you need to be monitored carefully for signs of muscle damage. Rhabdomyolysis usually causes bad muscle aches for no apparent reason, and can typically be diagnosed with a blood test for a muscle enzyme level.

    Liver abnormalities have been reported in some patients taking statins, but severe complications are very rare. Mild early abnormalities can be detected by taking periodic blood tests, and the medication can be stopped if the liver tests are significantly abnormal.

    Niacin (Niaspan and others) is another lipid-lowering medication. It has not been used as often in people with diabetes because of concerns that it might raise the blood sugar. However, sometimes it is very useful in patients with diabetes and can have a beneficial effect on the blood lipid levels.

    If you are a diabetic with high lipids, no matter what your treatment plan, there should be close communication between you, your doctor and the other health professionals involved in your care. Good communication is excellent insurance against adverse reactions.

    The good news if you have diabetes is that your risk of developing CAD can be dramatically lowered by taking lipid-lowering medication. Many clinical studies have now shown this. They have also confirmed that these medications are generally safe. The risk of getting heart disease without the medication is much greater than the risk of getting significant complications from the medication.

     






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